Aulabaugh, Ann: search on Z-Library

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1

PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease

Gopalsamy, Ariamala, Aulabaugh, Ann E., Barakat, Amey, Beaumont, Kevin C., Cabral, Shawn, Canterbury, Daniel P., Casimiro-Garcia, Agustin, Chang, Jeanne S., Chen, Ming Z., Choi, Chulho, Dow, Robert L.

Journal:

Journal of Medicinal Chemistry

Year:

2021

File:

PDF, 5.45 MB

2021

2

Chemical and Computational Methods for the Characterization of Covalent Reactive Groups for the Prospective Design of Irreversible Inhibitors

Flanagan, Mark E., Abramite, Joseph A., Anderson, Dennis P., Aulabaugh, Ann, Dahal, Upendra P., Gilbert, Adam M., Li, Chao, Montgomery, Justin, Oppenheimer, Stacey R., Ryder, Tim, Schuff, Brandon P.,

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 715 KB

english, 2014

3

Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery

Mei-Chu Lo, Ann Aulabaugh, Guixian Jin, Rebecca Cowling, Jonathan Bard, Michael Malamas, George Ellestad

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 369 KB

english, 2004

4

P2-337: Characterization of the affinity of GSI-953 for binding to gamma-secretase and comparison to benchmark gamma-secretase inhibitors

Kreft, Anthony F., Abou-Gharbia, Magid A., Aulabaugh, Ann E., Atchison, Kevin P., Diamantidis, George, Harrison, Boyd L., Hirst, Warren D., Huang, Xinyi, Kubrak, Dennis M., Lipinski, Kerri, Magolda, R

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 256 KB

english, 2008

5

Oxalyl hydroxamates as reaction-intermediate analogs for ketol-acid reductoisomerase

Aulabaugh, Ann, Schloss, John V.

Journal:

Year:

1990

Language:

english

File:

PDF, 880 KB

english, 1990

6

Design and synthesis of oxadiazolidinediones as inhibitors of plasminogen activator inhibitor-1

Ariamala Gopalsamy, Scott L. Kincaid, John W. Ellingboe, Thomas M. Groeling, Thomas M. Antrilli, Girija Krishnamurthy, Ann Aulabaugh, Gregory S. Friedrichs, David L. Crandall

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 266 KB

english, 2004

7

Acylguanidines as Small-Molecule β-Secretase Inhibitors

Cole, Derek C., Manas, Eric S., Stock, Joseph R., Condon, Jeffrey S., Jennings, Lee D., Aulabaugh, Ann, Chopra, Rajiv, Cowling, Rebecca, Ellingboe, John W., Fan, Kristi Y., Harrison, Boyd L., Hu, Yun,

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 244 KB

english, 2006

8

Synthesis of various chelating celluloses and their application in removing Al3+ from ATP

John V. Schloss, Georgianna Smith, Ann Aulabaugh, W.W. Cleland

Journal:

Analytical Biochemistry

Year:

1982

Language:

english

File:

PDF, 348 KB

english, 1982

9

A fluorescent assay suitable for inhibitor screening and vanin tissue quantification

Benfang H. Ruan, Derek C. Cole, Paul Wu, Amira Quazi, Karen Page, Jill F. Wright, Nelson Huang, Joseph R. Stock, Karl Nocka, Ann Aulabaugh, Rustem Krykbaev, Lori J. Fitz, Neil M. Wolfman, Margaret L.

Journal:

Analytical Biochemistry

Year:

2010

Language:

english

File:

PDF, 1.20 MB

english, 2010

10

Development and comparison of nonradioactive in vitro kinase assays for NIMA-related kinase 2

Guixian Jin, Ann Aulabaugh, Jennifer Pocas, Hao Liu, Ron Kriz, Deepak Sampath

Journal:

Analytical Biochemistry

Year:

2006

Language:

english

File:

PDF, 347 KB

english, 2006

11

Discovery and initial optimization of 5,5′-disubstituted aminohydantoins as potent β-secretase (BACE1) inhibitors

Pawel Nowak, Derek C. Cole, Ann Aulabaugh, Jonathan Bard, Rajiv Chopra, Rebecca Cowling, Kristi Y. Fan, Baihua Hu, Steve Jacobsen, Minakshi Jani, Guixan Jin, Mei-Chu Lo, Michael S. Malamas, Eric S. Ma

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 593 KB

english, 2010

12

DNA polymerase activity of hepatitis B virus particles: differential inhibition by l-enantiomers of nucleotide analogs

Michelle G. Davis, Jeanne E. Wilson, Nanine A. VanDraanen, Wayne H. Miller, George A. Freeman, Susan M. Daluge, Frank L. Boyd, Ann E. Aulabaugh, George R. Painter, Lawrence R. Boone

Journal:

Antiviral Research

Year:

1996

Language:

english

File:

PDF, 937 KB

english, 1996

13

Novel Modified Carboxy Terminal Fragments of Neuropeptide Y with High Affinity for Y2-Type Receptors and Potent Functional Antagonism at the Y1-Type Receptor

Leban, Johann J., Heyer, Dennis, Landavazo, Antonio, Matthews, Jessica, Aulabaugh, Ann, Daniels, Alejandro J.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 2.08 MB

english, 1995

14

Activation Loop Phosphorylation Modulates Bruton’s Tyrosine Kinase (Btk) Kinase Domain Activity

Lin, Laura, Czerwinski, Robert, Kelleher, Kerry, Siegel, Marshall M., Wu, Paul, Kriz, Ron, Aulabaugh, Ann, Stahl, Mark

Journal:

Year:

2009

Language:

english

File:

PDF, 1.19 MB

english, 2009

15

Human Immunodeficiency Virus Type-1 Reverse Transcriptase

Wilson, Jeanne E., Aulabaugh, Ann, Caligan, Brent, McPherson, Sylvia, Wakefield, John K., Jablonski, Sandra, Morrow, Casey D., Reardon, John E., Furman, Phillip A.

Journal:

Journal of Biological Chemistry

Year:

1996

Language:

english

File:

PDF, 309 KB

english, 1996

16

Lipidic peptides, I. Synthesis, resolution and structural elucidation of lipidic amino acids and their homo- and hetero-oligomers

William A. Gibbons, Richard A. Hughes, Mario Charalambous, Marika Christodoulou, Alice Szeto, Anne E. Aulabaugh, Paolo Mascagni, Istvan Toth

Journal:

European Journal of Organic Chemistry

Year:

1990

Language:

english

File:

PDF, 1013 KB

english, 1990

17

Design and Synthesis of Oxadiazolidinediones as Inhibitors of Plasminogen Activator Inhibitor-1.

Ariamala Gopalsamy, Scott L. Kincaid, John W. Ellingboe, Thomas M. Groeling, Thomas M. Antrilli, Girija Krishnamurthy, Ann Aulabaugh, Gregory S. Friedrichs, David L. Crandall

Journal:

Year:

2004

File:

PDF, 33 KB

2004

18

Synthesis, structure and stability of novel dimeric peptide-disulfides

JOHANN J. LEBAN, ANDREW SPALTENSTEIN, ANTONIO LANDAVAZO, WILLIAM CHESTNUT, ANN AULABAUGH, LESTER C.E. TAYLOR, ALEJANDRO J. DANIELS

Journal:

Chemical Biology & Drug Design

Year:

1996

Language:

english

File:

PDF, 543 KB

english, 1996

19

Cellular thermal shift and clickable chemical probe assays for the determination of drug-target engagement in live cells

Xu, Hua, Gopalsamy, Ariamala, Hett, Erik C., Salter, Shores, Aulabaugh, Ann, Kyne, Robert E., Pierce, Betsy, Jones, Lyn H.

Journal:

Organic & Biomolecular Chemistry

Year:

2016

Language:

english

File:

PDF, 355 KB

english, 2016

20

Characterization of Protein Kinase C θ Activation Loop Autophosphorylation and the Kinase Domain Catalytic Mechanism

Czerwinski, Robert, Aulabaugh, Ann, Greco, Rita M., Olland, Stephane, Malakian, Karl, Wolfrom, Scott, Lin, Laura, Kriz, Ron, Stahl, Mark, Huang, Ying, Liu, Lin, Chaudhary, Divya

Journal:

Year:

2005

Language:

english

File:

PDF, 200 KB

english, 2005

21

3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3

Lisa M. Havran, Dan C. Chong, Wayne E. Childers, Paul J. Dollings, Arlene Dietrich, Boyd L. Harrison, Vasilios Marathias, Gregory Tawa, Ann Aulabaugh, Rebecca Cowling, Bhupesh Kapoor, Weixin Xu, Lidia

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 739 KB

english, 2009

22

Kinetic Mechanism of Staphylococcus aureus Sortase SrtA

Huang, Xinyi, Aulabaugh, Ann, Ding, Weidong, Kapoor, Bhupesh, Alksne, Lefa, Tabei, Keiko, Ellestad, George

Journal:

Year:

2003

Language:

english

File:

PDF, 226 KB

english, 2003

23

Covalent Inhibitors of Interleukin-2 Inducible T Cell Kinase (Itk) with Nanomolar Potency in a Whole-Blood Assay

Zapf, Christoph W., Gerstenberger, Brian S., Xing, Li, Limburg, David C., Anderson, David R., Caspers, Nicole, Han, Seungil, Aulabaugh, Ann, Kurumbail, Ravi, Shakya, Subarna, Li, Xin, Spaulding, Vikki

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 2.52 MB

english, 2012

24

Rational approach to highly potent and selective apoptosis signal-regulating kinase 1 (ASK1) inhibitors

Lovering, Frank, Morgan, Paul, Allais, Christophe, Aulabaugh, Ann, Brodfuehrer, Joanne, Chang, Jeanne, Coe, Jotham, Ding, WeiDong, Dowty, Heather, Fleming, Margaret, Frisbie, Richard, Guzova, Julia, H

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 2.75 MB

english, 2017

25

Probing the Interaction of HTI-286 with Tubulin Using a Stilbene Analogue

Lo, Mei-Chu, Aulabaugh, Ann, Krishnamurthy, Girija, Kaplan, Joshua, Zask, Arie, Smith, Robert P., Ellestad, George

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 72 KB

english, 2004

26

Human Ras converting enzyme endoproteolytic specificity at the P2′ and P3′ positions of K-Ras-derived peptides

Irwin J Hollander, Eileen Frommer, Ann Aulabaugh, Robert Mallon

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2003

Language:

english

File:

PDF, 212 KB

english, 2003

27

Biochemical and Biophysical Characterization of Inhibitor Binding to Caspase-3 Reveals Induced Asymmetry

Aulabaugh, Ann, Kapoor, Bhupesh, Huang, Xinyi, Dollings, Paul, Hum, Wah-Tung, Banker, Annette, Wood, Andrew, Ellestad, George

Journal:

Year:

2007

Language:

english

File:

PDF, 332 KB

english, 2007

28

The Dual Role of Lipids of the Lipoproteins in Trumenba, a Self-Adjuvanting Vaccine Against Meningococcal Meningitis B Disease

Luo, Yin, Friese, Olga V., Runnels, Herbert A., Khandke, Lakshmi, Zlotnick, Gary, Aulabaugh, Ann, Gore, Thomas, Vidunas, Eugene, Raso, Stephen W., Novikova, Elena, Byrne, Emilia, Schlittler, Michael,

Journal:

The AAPS Journal

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

29

Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay

Hall, Justin, Brault, Amy, Vincent, Fabien, Weng, Shawn, Wang, Hong, Dumlao, Darren, Aulabaugh, Ann, Aivazian, Dikran, Castro, Dana, Chen, Ming, Culp, Jeffrey, Dower, Ken, Gardner, Joseph, Hawrylik, S

Journal:

Year:

2017

Language:

english

File:

PDF, 8.33 MB

english, 2017

30

A study of the interactions between residues in the C-terminal half of calmodulin by one and two-dimensional NMR methods and computer modelling

Ann AULABAUGH, Walter P. NIEMCZURA, Thomas L. BLUNDELL, William A. GIBBONS

Journal:

Year:

1984

Language:

english

File:

PDF, 835 KB

english, 1984

31

Inhibitors of Human Immunodeficiency Virus Type 1 Derived from gp41 Transmembrane Protein: Structure−Activity Studies

Kazmierski, Wieslaw M., Hazen, Richard J., Aulabaugh, Ann, StClair, Marty H.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 287 KB

english, 1996

32

Novel and Specific Respiratory Syncytial Virus Inhibitors That Target Virus Fusion

Ding, Wei-dong, Mitsner, Boris, Krishnamurthy, Girija, Aulabaugh, Ann, Hess, Cynthia D., Zaccardi, Joe, Cutler, Mark, Feld, Boris, Gazumyan, Anna, Raifeld, Yuri, Nikitenko, Antonia, Lang, Stanley A.,

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 127 KB

english, 1998

33

Binding screen for cystic fibrosis transmembrane conductance regulator correctors finds new chemical matter and yields insights into cystic fibrosis therapeutic strategy

Hall, Justin D., Wang, Hong, Byrnes, Laura J., Shanker, Suman, Wang, Kelong, Efremov, Ivan V., Chong, P. Andrew, Forman-Kay, Julie D., Aulabaugh, Ann E.

Journal:

Protein Science

Year:

2016

Language:

english

File:

PDF, 2.83 MB

english, 2016

34

Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Covalent Inhibitors

Casimiro-Garcia, Agustin, Trujillo, John I, Vajdos, Felix F., Juba, Brian M, Banker, Mary Ellen, Aulabaugh, Ann, Balbo, Paul, Bauman, Jonathan, Chrencik, Jill, Coe, Jotham W, Czerwinski, Robert M., Do

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.11 MB

english, 2018

35

Development of an HPLC assay for Staphylococcus aureus sortase: Evidence for the formation of the kinetically competent acyl enzyme intermediate

Ann Aulabaugh, Weidong Ding, Bhupesh Kapoor, Keiko Tabei, Lefa Alksne, Russ Dushin, Tracy Zatz, George Ellestad, Xinyi Huang

Journal:

Analytical Biochemistry

Year:

2007

Language:

english

File:

PDF, 720 KB

english, 2007

36

High field proton NMR studies of tryptic fragments of calmodulin: A comparison with the native protein

Ann Aulabaugh, Walter P. Niemczura, William A. Gibbons

Journal:

Biochemical and Biophysical Research Communications

Year:

1984

Language:

english

File:

PDF, 419 KB

english, 1984

37

A continuous and direct assay to monitor leucine-rich repeat kinase 2 activity

Silva, Rafael G., Geoghegan, Kieran F., Qiu, Xiayang, Aulabaugh, Ann

Journal:

Analytical Biochemistry

Year:

2014

Language:

english

File:

PDF, 1.81 MB

english, 2014

38

A New Experimental Method to Determine the Mutual Orientation of Helices in Coiled-Coil Proteins: Structural Information about the Dimeric Interface of cJun, cFos, GCN4, and gp41

Dr. Wieslaw M. Kazmierski, Dr. John McDermed, Dr. Ann Aulabaugh

Journal:

Chemistry - A European Journal

Year:

1996

Language:

english

File:

PDF, 1002 KB

english, 1996

39

Structural comparisons of meizothrombin and its precursor prothrombin in the presence or absence of procoagulant membranes

Pei, Gang, Laue, Thomas M., Aulabaugh, Ann, Fowlkes, Dana M., Lentz, Barry R.

Journal:

Year:

1992

Language:

english

File:

PDF, 910 KB

english, 1992

40

The confromational behaviour of the cardiac glycoside digoxin as indicated by NMR spectroscopy and molecular dynamics calculations

Ann E. Aulabaugh, Ronald C. Crouch, Gary E. Martin, Aris Ragouezeos, John P. Shockcor, Timothy D. Spitzer, R. Duncan Farrant, Brian D. Hudson, John C. Lindon

Journal:

Carbohydrate Research

Year:

1992

Language:

english

File:

PDF, 719 KB

english, 1992

41

Biophysical Characterization of the Interactions of HTI-286 with Tubulin Heterodimer and Microtubules

Krishnamurthy, Girija, Cheng, Wendy, Lo, Mei-Chu, Aulabaugh, Ann, Razinkov, Vladimir, Ding, WeiDong, Loganzo, Frank, Zask, Arie, Ellestad, George

Journal:

Year:

2003

Language:

english

File:

PDF, 371 KB

english, 2003

42

Engineered stabilization and structural analysis of the autoinhibited conformation of PDE4

Cedervall, Peder, Aulabaugh, Ann, Geoghegan, Kieran F., McLellan, Thomas J., Pandit, Jayvardhan

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.41 MB

english, 2015

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